The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes
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چکیده
منابع مشابه
The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes.
In the heart, inflammatory cytokines including interleukin (IL) 1β are implicated in regulating adaptive and maladaptive changes, whereas IL33 negatively regulates cardiomyocyte hypertrophy and promotes cardioprotection. These agonists signal through a common co-receptor but, in cardiomyocytes, IL1β more potently activates mitogen-activated protein kinases and NFκB, pathways that regulate gene ...
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ژورنال
عنوان ژورنال: Cytokine
سال: 2013
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2012.11.004